Pharmacokinetic Analysis of Plasma Theophylline
نویسندگان
چکیده
منابع مشابه
Mathematical Model of the Pharmacokinetic Behavior of Theophylline
Objective: To provide a further example which showed that a non-traditional mathematical modeling method based on the theory of dynamic systems can be successfully used for mathematical modeling pharmacokinetics. Method: The current study is a companion piece of the study by Kasuya., et al. [1]; published in December 1985 issue of the Journal of Pharmacokinetics and Biopharmaceutics, therefore ...
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The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...
متن کاملPharmacokinetic Behavior of Theophylline following PEEP in Critically Ill Patients with Acute Lung Injury
The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...
متن کاملPharmacokinetic Evaluation of Two Doses of Aminophylline/Theophylline Administered as Multiple Intermittent Infusions to Iranian Apneic Premature Neonates
Many premature neonates suffer from apnea, and aminophylline is administrated for them. The objective of this study was to reveal pharmacokinetic (PK) parameters of theophylline in Iranian premature neonates. Premature neonates (68) who were admitted in the Neonatal Intensive Care Unit (NICU) of Namazi, Hafez, and Zeinabieh Hospitals were included in the study. All of them received 5 mg/k...
متن کاملAnalysis of Plasma Concentrations of Theophylline in Smoking and Nonsmoking Patients with Asthma
BACKGROUND While dosing theophylline in asthmatics, we should consider that a lot of medicines, substances, conditions and diseases affect the clearance of theophylline, such as smoking, macrolide antibiotics, barbiturates, oral contraceptives, heart and liver insufficiency, alcohol, calcium-antagonists, pneumonia, viral infections, hypoxemia, etc. AIM The aim of the study is to investigate t...
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ژورنال
عنوان ژورنال: Japanese Journal of Hospital Pharmacy
سال: 1979
ISSN: 2185-9477,0389-9098
DOI: 10.5649/jjphcs1975.5.41